Innovative protocols validated
with scientific evidence

Osteocare European Project 

Release of VEGF from Dental Implant Surface Coated with Concentrated Growth Factors (CGF) and the Liquid Phase of CGF (LPCGF): In Vitro Results and Future Expectations

Andrea Palermo 1, Franco Ferrante 2, Eleonora Stanca 3, Fabrizio Damiano 3, Antonio Gnoni 4, Tiziano Batani 5, Maria Annunziata Carluccio 6, Christian Demitri 7 and Luisa Siculella 3 *

1. College of Medicine and Dentistry, B4 6BN Birmingham, UK; andrea.palermo2004@libero.it
2. Independent Researcher, 73100 Lecce, Italy; studioferrantelecce@gmail.com
3. Laboratory of Molecular Biology, Department of Biological and Environmental Sciences and Technologies. University of Salento, 73100 Lecce, Italy; stancanora@gmail.com  (E.S.); fabrizio.damiano@unisalento.it  (F.D.)
4. Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari “Aldo Moro”, 70124 Bari, Italy; antonio.gnoni@uniba.it
5. Silfradent srl, Via G. Di Vittorio n. 35/37, 47018 Santa Sofia (FC), Italy; t.batani@silfradent.com
6. National Research Council, Institute of Clinical Physiology, 73100 Lecce, Italy; maria.carluccio@ifc.cnr.it
7. Department of Engineering for Innovation, University of Salento, 73100 Lecce, Italy; christian.demitri@unisalento.it

* Correspondence: luisa.siculella@unisalento.it

Concentrated Growth Factors (CGF) Combined with Melatonin in Guided Bone Regeneration (GBR): a Case Report

Alessandro Leonida 1,†, Gaia Favero 2, 3, *, † , Paolo Caccianiga 1, Saverio Ceraulo 1, Luigi Fabrizio Rodella 2, 3, Rita Rezzani 2, 3, ‡ and Gianluigi Caccianiga 1, ‡

1. School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy. alessandro.leonida@unimib.it (A.L.); p.caccianiga@campus.unimib.it (P.C.); saverio.ceraulo@unimib.it (S.C.); gianluigi.caccianiga@unimib.it (G.C.)
2. Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy; luigi.rodella@unibs.it (L.F.R.); rita.rezzani@unibs.it (R.R.)
3. Interdipartimental University Center of Research “Adaption and Regeneration of Tissues and Organs-(ARTO)”, University of Brescia, 25123 Brescia, Italy

* Correspondence: gaia.favero@unibs.it; Tel.: +39-030-371-7479
† These authors contributed equally to this work.
‡ These authors contributed equally to this work.

Healing of alveolar sockets treated with concentrated growth factors: A split-mouth study

Marco Mozzati 1, Margherita Tumedei 2, Giorgia Gallesio 1, Giulio Menicucci 3, Carlo Manzella 3 , Tiziano Testori 2, 4, 5 and Massimo Del Fabbro 2, 4*

1. SIOM Oral Surgery and Implantology Center, 10126 Turin, Italy; marcomozzati@siompoliambulatorio.it  (M.M.); giorgiagallesio@siompoliambulatorio.it  (G.G.)
2. Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, 20122 Milan, Italy; margherita.tumedei@unimi.it  (M.T.) ; info@tiziano-testori.it  (T.T.)
3. Prosthodontic Department, School of Dentistry, University of Turin, 10124 Turin, Italy; giuliomenicucci@libero.it  (G.M.); carlo.manzella@studiosphera.it  (C.M.)
4. Dental Clinic, IRCCS Orthopedic Institute Galeazzi 20161 Milan, Italy
5. Department of Periodontics and Oral Medicine, The University of Michigan, School of Dentistry, Ann Arbor 48109, MI, USA;

* Correspondence: massimo.delfabbro@unimi.it; Tel.: +39-02-50319950

Activated Plasma Albumin Gel (APAG) in Transalveolar Technique for Maxillary Sinus Lift: A Case Series

Alessandro Leonida 1, Paolo Caccianiga 1,*, Ayt Alla Bader 1, Stefano Rosi 2, Saverio Ceraulo 1, Gianluigi Caccianiga 1

1. School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy
2. Independent Researcher, 60121 Ancona, Italy

* Correspondence: p.caccianiga@campus.unimib.it

Concentrated growth factor: a effective regenerative tool for soft and hard tissues in periodontics

Shaik Abdul Cader N M A 1 *, Snophia Suresh 2, Uma Sudhakar 3, Navina Ravindran 4, Roshini Rose A Paul 5

1. Postgraduate Student,
2. Professor,
3. Professor and Head,
4. Senior Lecturer,
5. Periodontist, Dept. of Periodontology, Thai Moogambigai Dental College and Hospital, Chennai, Tamil Nadu, India

* Corresponding Author: Shaik Abdul Cader [N M A] – Email: nmashaik@gmail.com

Lateral Sinus Floor Elevation in the Severely Atrophied Maxilla: Concentrated Growth Factors Versus Bone Substitutes: a controlled Clinical Trial

Mauro Merli, MD, DDS/Marco Moscatelli, DDS – Marco Merli, DDS – Giorgia Minotti, DDS – Umberto Pagliaro, MD, DDS, – Michele Nieri, DDS, PhD

The Multilayer GBR Technique: An Alternative Approach for One-Stage Transmucosal Implant Placement in the Presence of Horizontal Defects. A Case Series

Mauro Merli, MD, DDS/Marco Merli, DDS – Umberto Pagliaro, MD, DDS, – Adriano Fratini, DDS – Lucio Lo Russo, DDS, PhD – Michele Nieri, DDS, PhD